The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine

Abstract Despite the importance of immunity against neuraminidase (NA), NA content and immunogenicity are neglected in current influenza vaccines. To address this, a recombinant N1/N2 NA vaccine (NAV) was developed. Stability assays were used to determine optimal temperature and buffer conditions fo...

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Bibliographic Details
Main Authors: Luca T. Giurgea, Jae-Keun Park, Kathie-Anne Walters, Kelsey Scherler, Adriana Cervantes-Medina, Ashley Freeman, Luz Angela Rosas, John C. Kash, Jeffery K. Taubenberger, Matthew J. Memoli
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00310-x