Delivery of Thyronamines (TAMs) to the Brain: A Preliminary Study

Delivery of Thyronamines (TAMs) to the Brain: A Preliminary Study

Recent reports highlighted the significant neuroprotective effects of thyronamines (TAMs), a class of endogenous thyroid hormone derivatives. In particular, 3-iodothyronamine (T1AM) has been shown to play a pleiotropic role in neurodegeneration by modulating energy metabolism and neurological functi...

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Bibliographic Details
Main Authors: Nicoletta di Leo, Stefania Moscato, Marco Borso', Simona Sestito, Beatrice Polini, Lavinia Bandini, Agostina Grillone, Matteo Battaglini, Alessandro Saba, Letizia Mattii, Gianni Ciofani, Grazia Chiellini
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
3-iodothyronamine (T1AM)
multi-target directed ligand
neurodegeneration
blood–brain barrier
high-performance liquid chromatography coupled to mass spectrometry
Online Access:https://www.mdpi.com/1420-3049/26/6/1616

Internet

https://www.mdpi.com/1420-3049/26/6/1616

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