A conserved ZFX/WNT3 axis modulates the growth and imatinib response of chronic myeloid leukemia stem/progenitor cells

A conserved ZFX/WNT3 axis modulates the growth and imatinib response of chronic myeloid leukemia stem/progenitor cells

Abstract Background Zinc finger protein X-linked (ZFX) has been shown to promote the growth of tumor cells, including leukemic cells. However, the role of ZFX in the growth and drug response of chronic myeloid leukemia (CML) stem/progenitor cells remains unclear. Methods Real-time quantitative PCR (...

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Bibliographic Details
Main Authors: Xiuyan Zhang, Yu Wang, Jinchang Lu, Lun Xiao, Hui Chen, Quanxue Li, Yuan-Yuan Li, Peng Xu, Changgeng Ruan, Haixia Zhou, Yun Zhao
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cellular & Molecular Biology Letters
Subjects:
ZFX
WNT3
CD34+ cells
Chronic myeloid leukemia
Imatinib mesylate
Online Access:https://doi.org/10.1186/s11658-023-00496-z

Internet

https://doi.org/10.1186/s11658-023-00496-z

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