Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands

Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands

BackgroundCholinergic urticaria (CholU), a frequent form of chronic inducible urticaria, is characterized by itchy wheals and angioedema in response to sweating. As of now, the rate and pathophysiological relevance of impaired sweating in patients with CholU are ill-defined.AimTo assess in CholU pat...

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Bibliographic Details
Main Authors: Yiyu Wang, Jörg Scheffel, Carolina Ayala Vera, Wei Liu, Dorothee Günzel, Dorothea Terhorst-Molawi, Marcus Maurer, Sabine Altrichter
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
acetylcholine esterase
cholinergic
urticaria
muscarinic 3 receptor
sweat gland
wheal
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.955161/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.955161/full

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