Proof of concept for multiplex amplicon sequencing for mutation identification using the MinION nanopore sequencer

Abstract Rapid, cost-effective identification of genetic variants in small candidate genomic regions remains a challenge, particularly for less well equipped or lower throughput laboratories. The application of Oxford Nanopore Technologies’ MinION sequencer has the potential to fulfil this requireme...

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Bibliographic Details
Main Authors: Whitney Whitford, Victoria Hawkins, Kriebashne S. Moodley, Matthew J. Grant, Klaus Lehnert, Russell G. Snell, Jessie C. Jacobsen
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12613-7