Pseudomonas aeruginosa infection correlates with high MFI donor-specific antibody development following lung transplantation with consequential graft loss and shortened CLAD-free survival

Pseudomonas aeruginosa infection correlates with high MFI donor-specific antibody development following lung transplantation with consequential graft loss and shortened CLAD-free survival

Abstract Background Donor-specific antibodies (DSAs) are common following lung transplantation (LuTx), yet their role in graft damage is inconclusive. Mean fluorescent intensity (MFI) is the main read-out of DSA diagnostics; however its value is often disregarded when analyzing unwanted post-transpl...

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Bibliographic Details
Main Authors: Levente Zoltán Bogyó, Klára Török, Zsuzsanna Illés, Anikó Szilvási, Bálint Székely, Anikó Bohács, Orsolya Pipek, Ildikó Madurka, Zsolt Megyesfalvi, Ferenc Rényi-Vámos, Balázs Döme, Krisztina Bogos, Balázs Gieszer, Eszter Bakos
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Respiratory Research
Subjects:
Lung transplantation
DSA
HLA
AMR
CLAD
Pseudomonas aeruginosa
Online Access:https://doi.org/10.1186/s12931-024-02868-1

Internet

https://doi.org/10.1186/s12931-024-02868-1

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