Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles.
Influenza viruses are a major public health burden during seasonal epidemics and a continuous threat due to their potential to cause pandemics. Annual vaccination provides the best protection against the contagious respiratory illness caused by influenza viruses. However, the current production capa...
Main Authors: | Timo Frensing, Frank Stefan Heldt, Antje Pflugmacher, Ilona Behrendt, Ingo Jordan, Dietrich Flockerzi, Yvonne Genzel, Udo Reichl |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24039749/pdf/?tool=EBI |
Similar Items
-
Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals.
by: Frank S Heldt, et al.
Published: (2013-01-01) -
Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling
by: Felipe Tapia, et al.
Published: (2019-10-01) -
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
by: Marc D. Hein, et al.
Published: (2021-05-01) -
Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
by: Tanya Dogra, et al.
Published: (2023-11-01) -
A system for production of defective interfering particles in the absence of infectious influenza A virus.
by: Najat Bdeir, et al.
Published: (2019-01-01)