Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats

Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats

Parkinson's disease (PD) is the gradual and selective degradation of dopamine-releasing neurons in substantia nigra pars compacta (SNpc) and results in postural instability, stiffness, bradykinesia, and resting tremor. The goal of this research was to see how hibiscetin action on PD in rotenone...

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Bibliographic Details
Main Authors: Sami I. Alzarea, Muhammad Afzal, Khalid Saad Alharbi, Abdulaziz I. Alzarea, Sattam Khulaif Alenezi, Mohammed Salem Alshammari, Ali Alquraini, Imran Kazmi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Saudi Pharmaceutical Journal
Subjects:
Flavonoids
Hibiscetin
Neurodegeneration
Neuroinflammation
Neuroprotective
Online Access:http://www.sciencedirect.com/science/article/pii/S131901642200247X

Internet

http://www.sciencedirect.com/science/article/pii/S131901642200247X

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