Silicone rubber sealed channel induced self-healing of large bone defects: Where is the limit of self-healing of bone?

Background: Large defects of long tubular bones due to severe trauma, bone tumor resection, or osteomyelitis debridement are challenging in orthopedics. Bone non-union and other complications often lead to serious consequences. At present, autologous bone graft is still the gold standard for the tre...

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Bibliographic Details
Main Authors: Feng Gu, Ke Zhang, Wan-an Zhu, Zhenjiang Sui, Jiangbi Li, Xiaoping Xie, Tiecheng Yu
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X23000621