Circulating NPTX2 methylation as a non-invasive biomarker for prognosis and monitoring of metastatic pancreatic cancer

Circulating NPTX2 methylation as a non-invasive biomarker for prognosis and monitoring of metastatic pancreatic cancer

Abstract Background Pancreatic cancer is the most lethal cancer with a dismal prognosis mainly due to diagnosis at advanced stage and ineffective treatments. CA19-9 levels and computed tomography (CT) imaging are the main standard criteria for evaluating disease progression and treatment response. I...

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Main Authors: María Victoria García-Ortiz, Pablo Cano-Ramírez, Marta Toledano-Fonseca, María Teresa Cano, Elizabeth Inga-Saavedra, Rosa María Rodríguez-Alonso, Silvia Guil-Luna, María Auxiliadora Gómez-España, Antonio Rodríguez-Ariza, Enrique Aranda
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Clinical Epigenetics
Subjects:
NPTX2
Pancreatic ductal adenocarcinoma
Prognostic biomarker
Epigenetic biomarker
Liquid biopsy
DNA methylation
Online Access:https://doi.org/10.1186/s13148-023-01535-4

Internet

https://doi.org/10.1186/s13148-023-01535-4

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