Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation

Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation

Abstract Embryonic development is dependent on the maternal supply of proteins through the oocyte, including factors setting up the adequate epigenetic patterning of the zygotic genome. We previously reported that one such factor is the epigenetic repressor SMCHD1, whose maternal supply controls aut...

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Bibliographic Details
Main Authors: Iromi Wanigasuriya, Sarah A. Kinkel, Tamara Beck, Ellise A. Roper, Kelsey Breslin, Heather J. Lee, Andrew Keniry, Matthew E. Ritchie, Marnie E. Blewitt, Quentin Gouil
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Epigenetics & Chromatin
Online Access:https://doi.org/10.1186/s13072-022-00458-3

Internet

https://doi.org/10.1186/s13072-022-00458-3

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