Estradiol (E2) Improves Glucose-Stimulated Insulin Secretion and Stabilizes GDM Progression in a Prediabetic Mouse Model

Estradiol (E2) Improves Glucose-Stimulated Insulin Secretion and Stabilizes GDM Progression in a Prediabetic Mouse Model

Female New Zealand obese (NZO) mice are an established model of preconceptional (pc.) prediabetes that progresses as gestational diabetes mellitus (GDM) during gestation. It is known that NZO mice show improvement in insulin sensitivity and glucose-stimulated insulin secretion (GSIS) during gestatio...

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Bibliographic Details
Main Authors: Moritz Liebmann, Melissa Asuaje Pfeifer, Katharina Grupe, Stephan Scherneck
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
estradiol
prediabetes
gestational diabetes
liver
pancreas
multi-organ disease
Online Access:https://www.mdpi.com/1422-0067/23/12/6693

Internet

https://www.mdpi.com/1422-0067/23/12/6693

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