Enhancement of The Stability of Human Growth Hormone by Using Tris(hydroxymethyl)aminomethane: Molecular Docking and Experimental Analysis

Objective: It is so difficult to formulate human growth hormone (hGH) in a solution with high stability and new drug delivery system (NDDs) due to physiochemical instability. The purpose of this study was to investigate the possibility of using Tris as a hGH stabilizer. Materials and Methods: In...

Full description

Bibliographic Details
Main Authors: Siyavash Mirzaei, Hamid Mobedi, Hamid Gourabi, Mohammad Hosein Sanati, Sakine Khezli, Hamid Omidian, Masoume Ighaeie
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2021-01-01
Series:Cell Journal
Subjects:
Online Access:https://celljournal.org/journal/article/fulltext/enhanced-stability-of-the-human-growth-hormone-by-tris-hydroxymethyl-aminomethane-hcl-molecular-docking-modeling-and-experimental-analysis.pdf