Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

Abstract Neurologic disorders often disproportionately affect specific brain regions, and different apoptotic mechanisms may contribute to white matter pathology in leukodystrophies or gray matter pathology in poliodystrophies. We previously showed that neural progenitors that generate cerebellar gr...

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Bibliographic Details
Main Authors: Abigail H. Cleveland, Alejandra Romero-Morales, Laurent Alfonso Azcona, Melisa Herrero, Viktoriya D. Nikolova, Sheryl Moy, Orna Elroy-Stein, Vivian Gama, Timothy R. Gershon
Format: Article
Language:English
Published: Nature Publishing Group 2021-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04422-z

Internet

https://doi.org/10.1038/s41419-021-04422-z

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