In Silico Investigation of Traditional Chinese Medicine for Potential Lead Compounds as SPG7 Inhibitors against Coronary Artery Disease

In Silico Investigation of Traditional Chinese Medicine for Potential Lead Compounds as SPG7 Inhibitors against Coronary Artery Disease

Coronary artery disease (CAD) is the most common cause of heart attack and the leading cause of mortality in the world. It is associated with mitochondrial dysfunction and increased level of reactive oxygen species production. According to the Ottawa Heart Genomics Study genome-wide association stud...

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Bibliographic Details
Main Authors: Kuen-Bao Chen, Kuan-Chung Chen, Ya-Lin Chang, Kun-Lung Chang, Pei-Chun Chang, Tung-Ti Chang, Yu-Chian Chen
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
spastic paraplegia 7 (SPG7)
Traditional Chinese Medicine (TCM)
docking
molecular dynamics (MD) simulation
Online Access:http://www.mdpi.com/1420-3049/21/5/588

Internet

http://www.mdpi.com/1420-3049/21/5/588

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