D2 Plot, a Matrix of DNA Density and Distance to Periphery, Reveals Functional Genome Regions

D2 Plot, a Matrix of DNA Density and Distance to Periphery, Reveals Functional Genome Regions

Abstract The execution of biological activities inside space‐limited cell nuclei requires sophisticated organization. Current studies on the 3D genome focus on chromatin interactions and local structures, e.g., topologically associating domains (TADs). In this study, two global physical properties:...

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Bibliographic Details
Main Authors: Yizhuo Che, Xiaofei Yang, Peng Jia, Tingjie Wang, Dan Xu, Tianxue Guo, Kai Ye
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Advanced Science
Subjects:
3D genome
DNA density
nuclear lamina
single‐cell Hi‐C
Online Access:https://doi.org/10.1002/advs.202202149

Internet

https://doi.org/10.1002/advs.202202149

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