D2 Plot, a Matrix of DNA Density and Distance to Periphery, Reveals Functional Genome Regions
Abstract The execution of biological activities inside space‐limited cell nuclei requires sophisticated organization. Current studies on the 3D genome focus on chromatin interactions and local structures, e.g., topologically associating domains (TADs). In this study, two global physical properties:...
Main Authors: | Yizhuo Che, Xiaofei Yang, Peng Jia, Tingjie Wang, Dan Xu, Tianxue Guo, Kai Ye |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-10-01
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Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202202149 |
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