Transcriptomic profiling of canine decidualization and effects of antigestagens on decidualized dog uterine stromal cells

Abstract Maternal-stroma derived decidual cells, the only cell population in the canine placenta expressing the nuclear progesterone (P4) receptor (PGR), are crucial for the maintenance of canine pregnancy. Decreased circulating progesterone (P4) levels, or blockage of PGR function with antigestagen...

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Bibliographic Details
Main Authors: Miguel Tavares Pereira, Ali Kazemian, Hubert Rehrauer, Mariusz P. Kowalewski
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24790-6