Microinvasive pars plana vitrectomy combined with internal limiting membrane peeling versus anti-VEGF intravitreal injection for treatment-naïve diabetic macular edema (VVV-DME study): study protocol for a randomized controlled trial

Abstract Background Diabetic macular edema (DME) is the main cause of vision loss in diabetic patients. Currently, anti-vascular endothelial growth factor (VEGF) intravitreal injection stands as the first-line therapy for DME. However, some patients exhibit insufficient response to anti-VEGF agents...

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Bibliographic Details
Main Authors: Haoxin Guo, Wenbo Li, Zetong Nie, Xiang Zhang, Mingfei Jiao, Siqiong Bai, Naxin Duan, Xiaorong Li, Bojie Hu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-023-07735-w