Key therapeutic targets implicated at the early stage of hepatocellular carcinoma identified through machine-learning approaches

Abstract Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer. Early-stage detection plays an essential role in making treatment decisions and identifying dominant molecular mechanisms. We utilized machine learning algorithms to find significant mRNAs and microRNAs (miRNA...

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Bibliographic Details
Main Authors: Seyed Mahdi Hosseiniyan Khatibi, Farima Najjarian, Hamed Homaei Rad, Mohammadreza Ardalan, Mohammad Teshnehlab, Sepideh Zununi Vahed, Saeed Pirmoradi
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30720-x