The Synthesis and Evaluation of Diethyl Benzylphosphonates as Potential Antimicrobial Agents

The Synthesis and Evaluation of Diethyl Benzylphosphonates as Potential Antimicrobial Agents

The impact of substituent at phenyl ring of diethyl benzylphosphonate derivatives on cytotoxic activity was studied. The organophosphonates were obtained based on developed palladium-catalyzed α, β-homodiarylation of vinyl esters protocol. The new synthetic pathway toward 1,2-bis(4-((diethoxyphospho...

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Bibliographic Details
Main Authors: Anna Brodzka, Paweł Kowalczyk, Damian Trzepizur, Dominik Koszelewski, Karol Kramkowski, Mateusz Szymczak, Aleksandra Wypych, Rafał Lizut, Ryszard Ostaszewski
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
benzylphosphonates
antimicrobial activity
Fpg protein-formamidopyrimidine
lipopolysaccharide (LPS)
Online Access:https://www.mdpi.com/1420-3049/27/20/6865

Internet

https://www.mdpi.com/1420-3049/27/20/6865

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