Inferring the three-dimensional structures of the X-chromosome during X-inactivation

The Hi-C experiment can capture the genome-wide spatial proximities of the DNA, based on which it is possible to computationally reconstruct the three-dimensional (3D) structures of chromosomes. The transcripts of the long non-coding RNA (lncRNA) Xist spread throughout the entire X-chromosome and al...

Descrición completa

Detalles Bibliográficos
Main Authors: Hao Zhu, Nan Wang, Jonathan Z. Sun, Ras B. Pandey, Zheng Wang
Formato: Artigo
Idioma:English
Publicado: AIMS Press 2019-08-01
Series:Mathematical Biosciences and Engineering
Subjects:
Acceso en liña:https://www.aimspress.com/article/10.3934/mbe.2019369?viewType=HTML