Hexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathway

Hexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathway

Abstract Introduction Hexarelin exhibits significant protection against organ injury in models of ischemia/reperfusion (I/R)-induced injury (IRI). Nevertheless, the impact of Hexarelin on acute kidney injury (AKI) and its underlying mechanism remains unclear. In this study, we investigated the thera...

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Bibliographic Details
Main Authors: Chen Guan, Chenyu Li, Xuefei Shen, Chengyu Yang, Zengying Liu, Ningxin Zhang, Lingyu Xu, Long Zhao, Bin Zhou, Xiaofei Man, Congjuan Luo, Hong Luan, Lin Che, Yanfei Wang, Yan Xu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:European Journal of Medical Research
Subjects:
Acute kidney injury
Kidney ischemia–reperfusion injury
Hexarelin
Apoptosis
MDM2/p53
Online Access:https://doi.org/10.1186/s40001-023-01318-w

Internet

https://doi.org/10.1186/s40001-023-01318-w

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