Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice

Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice

Abstract Background Maternal obesity alters oocytes and subsequent fetal metabolism. An increasing number of studies have shown that the endoplasmic reticulums (ER) or mitochondria have important effects on oocyte quality, but there has been no study of the effect of mitochondria-associated ER membr...

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Bibliographic Details
Main Authors: Lihong Zhao, Tengfei Lu, Lei Gao, Xiangwei Fu, Shien Zhu, Yunpeng Hou
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Apoptosis
IP3R1
MAM
Mitochondrial Ca2+
Obesity
Oocyte
Online Access:http://link.springer.com/article/10.1186/s40104-017-0195-z

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http://link.springer.com/article/10.1186/s40104-017-0195-z

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