Pan-cancer and single-cell analyses identify CD44 as an immunotherapy response predictor and regulating macrophage polarization and tumor progression in colorectal cancer
IntroductionCluster of differentiation (CD) 44 is a non-kinase cell surface transmembrane glycoprotein critical for tumor maintenance and progression.MethodsWe conducted a systematic analysis of the expression profile and genomic alteration profile of CD44 in 33 types of cancer. The immune character...
Main Authors: | Qian Zhang, Xinyu Wang, Yang Liu, Hao Xu, Chun Ye |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2024-03-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1380821/full |
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