Involvement of endothelium in the vasorelaxant effects of 3,4-DHPEA-EA and 3,4-DHPEA-EDA, two major functional bioactives in olive oil

Involvement of endothelium in the vasorelaxant effects of 3,4-DHPEA-EA and 3,4-DHPEA-EDA, two major functional bioactives in olive oil

The olive oil polyphenols 3,4-DHPEA-EA and 3,4-DHPEA-EDA displayed an endothelium-dependent vasorelaxant effect in rat aorta, starting at ~1 µM and abolished by NG-nitro-L-arginine (L-NA) or N-acetylcysteine, and an endothelium-independent vasorelaxant effect, starting at ~10 µM. Hydroxytyrosol only...

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Bibliographic Details
Main Authors: María Segade, Roberto Bermejo, Aníbal Silva, Fátima Paiva-Martins, José Gil-Longo, Manuel Campos-Toimil
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Functional Foods
Subjects:
Endothelium
Nitric oxide
Olive oil
Polyphenols
Vasorelaxant
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616300457

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http://www.sciencedirect.com/science/article/pii/S1756464616300457

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