Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis

Abstract Background Pyroptosis is a novel programmed cell death. It is identified as caspase-1 dependent and characterized by plasma-membrane rupture and release of proinflammatory intracellular contents inculuding IL-1 beta and IL-18. Pyroptosis is distinct from other forms of cell death, especiall...

Full description

Bibliographic Details
Main Authors: Xin Zeng, Min Zhu, Xiaohong Liu, Xuanmin Chen, Yujia Yuan, Lan Li, Jingping Liu, Yanrong Lu, Jingqiu Cheng, Younan Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Nutrition & Metabolism
Subjects:
Pyroptosis
ER stress
Lipotoxicity
Oleic acid
Palmitic acid
Online Access:https://doi.org/10.1186/s12986-020-0434-8

Internet

https://doi.org/10.1186/s12986-020-0434-8

Similar Items