Mitochondrial Fission Inhibitors Suppress Endothelin-1-Induced Artery Constriction

Mitochondrial Fission Inhibitors Suppress Endothelin-1-Induced Artery Constriction

Background/Aims: Endothelin-1 is implicated in the pathogenesis of hypertension, but the underlying mechanisms remained elusive. Our previous study found that inhibition of mitochondrial fission of smooth muscle cells suppressed phenylephrine- and high K+-induced artery constriction. Here, we studie...

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Bibliographic Details
Main Authors: Chang Chen, Jin-Lai Gao, Ming-Yu Liu, Shan-Liang Li, Xiu-Chen Xuan, Xin-Zi Zhang, Xi-Yue Zhang, Yuan-Yuan Wei, Chang-Lin Zhen, Jing Jin, Xin Shen, De-Li Dong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Endothelin-1
Mdivi-1
Vascular smooth muscle
Mitochondrial fission
Online Access:http://www.karger.com/Article/FullText/479536

Internet

http://www.karger.com/Article/FullText/479536

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