Pancreatic islet cell type–specific transcriptomic changes during pregnancy and postpartum

Pancreatic islet cell type–specific transcriptomic changes during pregnancy and postpartum

Summary: Pancreatic β-cell mass expands during pregnancy and regresses in the postpartum period in conjunction with dynamic metabolic demands on maternal glucose homeostasis. To understand transcriptional changes driving these adaptations in β-cells and other islet cell types, we performed single-ce...

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Bibliographic Details
Main Authors: Jin-Yong Chung, Yongjie Ma, Dingguo Zhang, Hayden H. Bickerton, Eric Stokes, Sweta B. Patel, Hubert M. Tse, Joseph Feduska, Rob S. Welner, Ronadip R. Banerjee
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Pregnancy
Molecular physiology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223005163

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http://www.sciencedirect.com/science/article/pii/S2589004223005163

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