Dissection of Functional Residues in Receptor Activity-Modifying Proteins Through Phylogenetic and Statistical Analyses

Type I and type-II functional divergences have been stated to highlight specific residues carrying out differential functions in evolutionary-divergent protein clusters from a single common ancestor. Briefly, type I analysis is based on residue constraints reflecting a gain of function just in one clus...

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Bibliographic Details
Main Authors: Alfonso Benítez-Páez, Sonia Cárdenas-Brito
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Evolutionary Bioinformatics
Subjects:
Online Access:http://la-press.com/article.php?article_id=756