Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila
Abstract Sleep and circadian rhythm disruptions are frequent comorbidities of Parkinson’s disease (PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. However, the causal role of circadian clocks in the degenerative process remains uncertain. W...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41540-y |