Splenic macrophages as the source of bacteraemia during pneumococcal pneumonia

Splenic macrophages as the source of bacteraemia during pneumococcal pneumonia

Background: Severe community-acquired pneumococcal pneumonia is commonly associated with bacteraemia. Although it is assumed that the bacteraemia solely derives from pneumococci entering the blood from the lungs it is unknown if other organs are important in the pathogenesis of bacteraemia. Using th...

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Bibliographic Details
Main Authors: David Carreno, Joseph J Wanford, Zydrune Jasiunaite, Ryan G. Hames, Wen Y Chung, Ashley R. Dennison, Kornelis Straatman, Luisa Martinez-Pomares, Manish Pareek, Carlos J. Orihuela, Marcos I. Restrepo, Wei Shen Lim, Peter W. Andrew, E. Richard Moxon, Marco R Oggioni
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:EBioMedicine
Subjects:
Bacteraemia
sepsis
human organ
pathogenesis
pneumonia
therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003947

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http://www.sciencedirect.com/science/article/pii/S2352396421003947

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