Synergistic therapeutic effects of intracerebral transplantation of human modified bone marrow-derived stromal cells (SB623) and voluntary exercise with running wheel in a rat model of ischemic stroke

Synergistic therapeutic effects of intracerebral transplantation of human modified bone marrow-derived stromal cells (SB623) and voluntary exercise with running wheel in a rat model of ischemic stroke

Abstract Background Mesenchymal stromal cell (MSC) transplantation therapy is a promising therapy for stroke patients. In parallel, rehabilitation with physical exercise could ameliorate stroke-induced neurological impairment. In this study, we aimed to clarify whether combination therapy of intrace...

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Bibliographic Details
Main Authors: Satoru Yabuno, Takao Yasuhara, Takayuki Nagase, Satoshi Kawauchi, Chiaki Sugahara, Yosuke Okazaki, Kakeru Hosomoto, Susumu Sasada, Tatsuya Sasaki, Naoki Tajiri, Cesar V. Borlongan, Isao Date
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Stem Cell Research & Therapy
Subjects:
Cerebral ischemic infarct
Rehabilitation
Regenerative medicine
SB623
Voluntary exercise
Online Access:https://doi.org/10.1186/s13287-023-03236-4

Internet

https://doi.org/10.1186/s13287-023-03236-4

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