GHRH-stimulated pituitary small extracellular vesicles inhibit hepatocyte proliferation and IGF-1 expression by its cargo miR-375-3p

GHRH-stimulated pituitary small extracellular vesicles inhibit hepatocyte proliferation and IGF-1 expression by its cargo miR-375-3p

Abstract Small extracellular vesicles (sEV) have emerged as a novel mode of intercellular material transport and information transmission. It has been suggested hormones may regulate the production and function of sEV. However, the specific impact of growth hormone-releasing hormone (GHRH) on pituit...

Full description

Bibliographic Details
Main Authors: Jiali Xiong, Yuxuan Wang, Hailong Wang, Junyi Luo, Ting Chen, Jiajie Sun, Qianyun Xi, Yongliang Zhang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Nanobiotechnology
Subjects:
GHRH
Pituitary small extracellular vesicles
Hepatocyte
miR-375-3p
IGF-1
Online Access:https://doi.org/10.1186/s12951-024-02857-y

Internet

https://doi.org/10.1186/s12951-024-02857-y

Similar Items