Liposomes Composed by Membrane Lipid Extracts from Macrophage Cell Line as a Delivery of the Trypanocidal <i>N</i>,<i>N</i>’-Squaramide 17 towards <i>Trypanosoma cruzi</i>

Liposomes Composed by Membrane Lipid Extracts from Macrophage Cell Line as a Delivery of the Trypanocidal <i>N</i>,<i>N</i>’-Squaramide 17 towards <i>Trypanosoma cruzi</i>

Chagas is a neglected tropical disease caused by <i>Trypanosoma cruzi</i>, and affects about 25 million people worldwide. <i>N</i>, <i>N</i>’-Squaramide 17 (S) is a trypanocidal compound with relevant in vivo effectiveness. Here, we produced, characterized, and ev...

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Bibliographic Details
Main Authors: Christian Rafael Quijia, Cínthia Caetano Bonatto, Luciano Paulino Silva, Milene Aparecida Andrade, Clenia Santos Azevedo, Camila Lasse Silva, Manel Vega, Jaime Martins de Santana, Izabela Marques Dourado Bastos, Marcella Lemos Brettas Carneiro
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Materials
Subjects:
Chagas
trypanocidal effect
cytotoxicity
nanostructures
mimetic lipid membrane
Online Access:https://www.mdpi.com/1996-1944/13/23/5505

Internet

https://www.mdpi.com/1996-1944/13/23/5505

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