Polysaccharides from Tumorous stem mustard prevented high fructose diet-induced non-alcoholic fatty liver disease by regulating gut microbiota, hepatic lipid metabolism, and the AKT/FOXO1/MAPK signaling pathway

Polysaccharides from Tumorous stem mustard prevented high fructose diet-induced non-alcoholic fatty liver disease by regulating gut microbiota, hepatic lipid metabolism, and the AKT/FOXO1/MAPK signaling pathway

Ingestion of 30 % fructose water (HF) for eight weeks caused non-alcoholic fatty liver disease (NAFLD) in mice and manifested in prominent weight gain, insulin resistance, abnormal lipid metabolism, oxidative stress, and liver damage. Biochemical analysis suggested that treatment with non-starch pol...

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Bibliographic Details
Main Authors: Changman Li, Wenfeng Li, Hongyan Yang, Zhenzhen Mi, Si Tan, Xin Lei
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Functional Foods
Subjects:
Brassica juncea var. tumida
Dyslipidemia
Pathoglycemia
Metabonomics
Gut microbiota
Transcriptome
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623000488

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http://www.sciencedirect.com/science/article/pii/S1756464623000488

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