Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A viruses

<p>Abstract</p> <p>Chloroquine is a 4-aminoquinoline previously used in malaria therapy and now becoming an emerging investigational antiviral drug due to its broad spectrum of antiviral activities. To explore whether the low pH-dependency of influenza A viruses might affect the an...

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Bibliographic Details
Main Authors: Vignolo Edoardo, D'Ostilio Daniela, Puzelli Simona, Norelli Sandro, Campitelli Laura, Savarino Andrea, Di Trani Livia, Donatelli Isabella, Cassone Antonio
Format: Article
Language:English
Published: BMC 2007-05-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/4/1/39