Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress

Abstract Stress increases plasma concentrations of corticosteroids, however, their tissue levels are unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress on tissue levels of corticosterone (CORT), progesterone (PROG), 11-deoxycorticosterone (11DOC) and 11-dehydr...

Full description

Bibliographic Details
Main Authors: Karla Vagnerová, Michal Jágr, Chahrazed Mekadim, Peter Ergang, Hana Sechovcová, Martin Vodička, Kateřina Olša Fliegerová, Václav Dvořáček, Jakub Mrázek, Jiří Pácha
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34395-2