Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress
Abstract Stress increases plasma concentrations of corticosteroids, however, their tissue levels are unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress on tissue levels of corticosterone (CORT), progesterone (PROG), 11-deoxycorticosterone (11DOC) and 11-dehydr...
Main Authors: | Karla Vagnerová, Michal Jágr, Chahrazed Mekadim, Peter Ergang, Hana Sechovcová, Martin Vodička, Kateřina Olša Fliegerová, Václav Dvořáček, Jakub Mrázek, Jiří Pácha |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-34395-2 |
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