Combining photothermal ablation-based vaccine with immune checkpoint blockade for synergistic osteosarcoma immunotherapy

Combining photothermal ablation-based vaccine with immune checkpoint blockade for synergistic osteosarcoma immunotherapy

Osteosarcoma is a serious bone malignancy that threatens to human health, while the conventional chemotherapy exhibits ineffective and severe side effects. Here, a multi-approach for primary and metastatic tumors was developed by combining photothermal ablation-based in situ tumor vaccine with PD-1/...

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Bibliographic Details
Main Authors: Xingyu Zhao, Yu Han, Yang Sun, Wei Feng, Jianguo Liu, Dongsong Li, Tiejun Wang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Materials & Design
Subjects:
Tumor vaccine
Immune checkpoint blockade
Osteosarcoma
Photothermal therapy
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127520308479

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