Kinome-Wide RNAi Screen Uncovers Role of Ballchen in Maintenance of Gene Activation by Trithorax Group in Drosophila

Kinome-Wide RNAi Screen Uncovers Role of Ballchen in Maintenance of Gene Activation by Trithorax Group in Drosophila

Polycomb group (PcG) and trithorax group (trxG) proteins are evolutionary conserved factors that contribute to cell fate determination and maintenance of cellular identities during development of multicellular organisms. The PcG maintains heritable patterns of gene silencing while trxG acts as anti-...

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Bibliographic Details
Main Authors: Muhammad Haider Farooq Khan, Jawad Akhtar, Zain Umer, Najma Shaheen, Ammad Shaukat, Muhammad Shahbaz Munir, Aziz Mithani, Saima Anwar, Muhammad Tariq
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
trithorax group
polycomb group
kinases
NHK-1
transcriptional memory
histone modifications
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.637873/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.637873/full

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