The Streptococcus pneumoniae pezAT toxin-antitoxin system reduces β-lactam resistance and genetic competence

Chromosomally-encoded Type II Toxin-Antitoxin operons are ubiquitous in bacteria and archaea. Antitoxins neutralize the toxic effect of cognate Toxins by protein-protein interactions and sequestering the active residues of the Toxin. Toxins target essential bacterial processes, mostly translation an...

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Bibliographic Details
Main Authors: Wai Ting Chan, Manuel Espinosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01322/full