Solubility Enhancement of Ibuprofen by Adsorption onto Spherical Porous Calcium Silicate

The solubility of a drug is higher when it is in an amorphous form than when it is in a crystalline form. To enhance the solubility of ibuprofen (IBU), a poorly water-soluble drug, we attempted to adsorb IBU onto spherical porous calcium silicate (Florite<sup>®</sup> PS300, PS300) in two...

Full description

Bibliographic Details
Main Authors: Yayoi Kawano, Shiyang Chen, Takehisa Hanawa
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/6/767