Using expression quantitative trait loci data and graph-embedded neural networks to uncover genotype–phenotype interactions

Motivation: A central goal of current biology is to establish a complete functional link between the genotype and phenotype, known as the so-called genotype–phenotype map. With the continuous development of high-throughput technology and the decline in sequencing costs, multi-omics analysis has beco...

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Bibliographic Details
Main Authors: Xinpeng Guo, Jinyu Han, Yafei Song, Zhilei Yin, Shuaichen Liu, Xuequn Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.921775/full