Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels

Abstract Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. Prdx1 catalyzes the reduction of H2O2 and alkyl hydroperoxide and plays an important role in different biological processes. Prdx1 also participates in various age-related diseases and cancers...

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Main Authors: Soomin Chae, Hyun-Kyung Lee, Yoo-Kyung Kim, Hyo Jung Sim, Yoorim Ji, Chowon Kim, Tayaba Ismail, Jeen-Woo Park, Oh-Shin Kwon, Beom-Sik Kang, Dong-Seok Lee, Jong-Sup Bae, Sang-Hyun Kim, Kyoung-Jin Min, Taeg Kyu Kwon, Mae-Ja Park, Jin-Kwan Han, Taejoon Kwon, Tae-Joo Park, Hyun-Shik Lee
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09262-6