Genetic Determinants of Hydrogen Sulfide Biosynthesis in Fusobacterium nucleatum Are Required for Bacterial Fitness, Antibiotic Sensitivity, and Virulence

ABSTRACT The Gram-negative anaerobe Fusobacterium nucleatum is a major producer of hydrogen sulfide (H2S), a volatile sulfur compound that causes halitosis. Here, we dissected the genetic determinants of H2S production and its role in bacterial fitness and virulence in this important member of the o...

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Bibliographic Details
Main Authors: Yi-Wei Chen, Martha I. Camacho, Yimin Chen, Aadil H. Bhat, Chungyu Chang, Emily A. Peluso, Chenggang Wu, Asis Das, Hung Ton-That
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01936-22