Higher incidence of co-expression of BCR-ABL fusion transcripts in an Eastern Indian population

Higher incidence of co-expression of BCR-ABL fusion transcripts in an Eastern Indian population

Abstract Background Chronic myeloid leukaemia (CML) is a haematopoietic stem cell disorder, caused by a balanced reciprocal translocation (t(9;22) (q34;q11)) that leads to the formation of BCR (Breakpoint Cluster Region)-ABL (Abelson) fusion transcripts known as Philadelphia (Ph) chromosome. The pre...

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Bibliografische gegevens
Hoofdauteurs: Ajeet Kumar, Vatsal Mishra, Chandra Bhan Singh, Rashmi Patel, Siddharth Samrat, Madhukar Rai, Nilesh Kumar, Vijay Tilak, Vineeta Gupta, Akhtar Ali
Formaat: Artikel
Taal:English
Gepubliceerd in: SpringerOpen 2023-10-01
Reeks:Egyptian Journal of Medical Human Genetics
Onderwerpen:
CML
Fusion transcripts
Translocation
qRT-PCR
Co-expression
Philadelphia chromosome
Online toegang:https://doi.org/10.1186/s43042-023-00435-9

Internet

https://doi.org/10.1186/s43042-023-00435-9

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