C9orf72 ALS mutation carriers show extensive cortical and subcortical damage compared to matched wild-type ALS patients

C9orf72 ALS mutation carriers show extensive cortical and subcortical damage compared to matched wild-type ALS patients

Objective: C9orf72 mutation carriers with different neurological phenotypes show cortical and subcortical atrophy in multiple different brain regions, even in pre-symptomatic phases. Despite there is a substantial amount of knowledge, small sample sizes, clinical heterogeneity, as well as different...

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Bibliographic Details
Main Authors: Anna Nigri, Manera Umberto, Mario Stanziano, Stefania Ferraro, Davide Fedeli, Jean Paul Medina Carrion, Sara Palermo, Laura Lequio, Federica Denegri, Federica Agosta, Massimo Filippi, Maria Consuelo Valentini, Antonio Canosa, Andrea Calvo, Adriano Chiò, Maria Grazia Bruzzone, Cristina Moglia
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Amyotrophic Lateral Sclerosis
C9orf72 mutation
MRI
fMRI
Online Access:http://www.sciencedirect.com/science/article/pii/S221315822300089X

Internet

http://www.sciencedirect.com/science/article/pii/S221315822300089X

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