Oropharyngeal administration of colostrum targeting gut microbiota and metabolites in very preterm infants: protocol for a multicenter randomized controlled trial

Abstract Background Oropharyngeal administration of colostrum (OAC) has an immune-stimulating effect on oropharyngeal-associated lymphoid tissue, and can promote the maturation of the gastrointestinal tract. However, how OAC promotes intestinal maturation in preterm infants by altering gut microbiot...

Full description

Bibliographic Details
Main Authors: Na Wang, Jia Zhang, Zhangbin Yu, Xudong Yan, Lian Zhang, Haibo Peng, Cheng Chen, Rui Li
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s12887-023-04346-x