Re-Expression of Poly/Oligo-Sialylated Adhesion Molecules on the Surface of Tumor Cells Disrupts Their Interaction with Immune-Effector Cells and Contributes to Pathophysiological Immune Escape

Re-Expression of Poly/Oligo-Sialylated Adhesion Molecules on the Surface of Tumor Cells Disrupts Their Interaction with Immune-Effector Cells and Contributes to Pathophysiological Immune Escape

Glycans linked to surface proteins are the most complex biological macromolecules that play an active role in various cellular mechanisms. This diversity is the basis of cell–cell interaction and communication, cell growth, cell migration, as well as co-stimulatory or inhibitory signaling. Our revie...

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Bibliographic Details
Main Authors: Mostafa Jarahian, Faroogh Marofi, Marwah Suliman Maashi, Mahnaz Ghaebi, Abdolrahman Khezri, Martin R. Berger
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
polysialylation
immune escape
electrostatic repulsion
adhesion molecules
apoptosis
metastasis
Online Access:https://www.mdpi.com/2072-6694/13/20/5203

Internet

https://www.mdpi.com/2072-6694/13/20/5203

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